Facile and simple preparation of pH-sensitive chitosan-mesoporous silica nanoparticles for future breast cancer treatment
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چکیده
منابع مشابه
Facile synthesis of pH sensitive polymer-coated mesoporous silica nanoparticles and their application in drug delivery.
pH-responsive polymer shell chitosan/poly (methacrylic acid) (CS-PMAA) was coated on mesoporous silica nanoparticles (MSN) through the facile in situ polymerization method. The resultant composite microspheres showed a flexible control over shell thickness, surface charges and hydrodynamic size by adjusting the feeding amount of MSN and the molar ratio of [-NH(2)]/MAA. The MSN/CS-PMAA composite...
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In this work core-shell structure Fe3O4@SiO2@meso-SiO2 microsphere has been successfully prepared. An inorganic magnetic core has been coated with multi-shell structure, dense nonporous silica as an inner layer and mesoporous silica as an outer layer. The dense silica shell can enhance the stability and minimize the negative effect of acidic condi...
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In the fight against cancer, controlled drug delivery systems have emerged to enhance the therapeutic efficacy and safety of anti-cancer drugs. Among these systems, mesoporous silica nanoparticles (MSNs) with a functional surface possess obvious advantages and were thus rapidly developed for cancer treatment. Many stimuli-responsive materials, such as nanoparticles, polymers, and inorganic mate...
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The application of nanotechnology to medicine constitutes a major field of research nowadays. In particular, the use of mesoporous silica and carbon nanoparticles has attracted the attention of numerous researchers due to their unique properties, especially when applied to cancer treatment. Many strategies based on stimuli-responsive nanocarriers have been developed to control the drug release ...
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Mesoporous silica has emerged as one of the most promising carriers for drug delivery systems. However, the synthesis of ultra-small mesoporous silica nanoparticles (UMSNs) and their application in drug delivery remains a significant challenge. Here, spherical UMSNs (∼25 nm) have been synthesized and tested as drug carriers. Anti-cancer drugs mitoxantrone (MX), doxorubicin (DOX) and methotrexat...
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ژورنال
عنوان ژورنال: Express Polymer Letters
سال: 2015
ISSN: 1788-618X
DOI: 10.3144/expresspolymlett.2015.96